Minor Sawyer spoiler and much speculation behind LJ-cut:
Jack is reluctant to help Sawyer when he begins to suffer from excruciating headaches.
What does it mean? Something seriously wrong with Sawyer? (Augh!) At the very least more Jack/Sawyer interaction, which you know I'm happy about. Could even be kind of funny, I guess. As long as it's nothing serious. (Prepares poison apple for Bad Robot if anything happens to Sawyer!)
And I happen to have a headache myself, just now. Cause for concern? Dundundun...